科研团队

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王克坚

教授

Dr. Wang Kejian
Minjiang Chair Professor

Email: wkjian@xmu.edu.cn

个人履历 Brief CV

"闽江学者"特聘教授 (2009-)

美国佛罗里达大学生理学与功能基因系高级访问学者 (2005-2006)

厦门大学教授(2001-)

中国农业科学院特产研究所研究员(2000-2001)

中国人民解放军军需大学博士(1999)

澳大利亚悉尼大学动物健康系访问学者(1993-1994)

Mingjiang chair professor, Xiamen University (2009-)

Senior Visiting Scholar, Department of Physiology and Functional Genomics, University of Florida, USA (2005-2006)

Professor, Xiamen University (2001-)

Senior Principal Research Fellow, Chinese Academy of Agricultural Sciences (2000-2001)

PhD, Quartermaster University of PLA (1999)

Visiting Scholar, Department of Animal Health, University of Sydney, Australia (1993-1994)

研究方向 Research Interests

海洋生物分子生物学与基因组学
海洋环境污染物的分子与免疫毒理学
转基因与基因工程
(Marine Molecular Biology and Genomics )
(Molecular and Immunological Ecotoxicology Studies for the Marine Environmental Pollutants )
(Transgenic and Genetic Engineering Studies)

代表性论文 Selected Publications

Zhou, Z.Z., Chen, F.Y.*, Hao, H.,Ke-Jian Wang* , A novel antimicrobial peptide Larimicin78-102 from large yellow croaker (Larimichthys crocea) shows potent antibacterial activity in vitro and enhances resistance to vibrio fluvialis infection in vivo, Fish and Shellfish Immunology 161 (2025) 110279.

Meng, X.Z., Duan, Y.Y., Bai, Y.Q., Zhang, W.B., Zhang, C., Chen, F.Y.*, Ke-Jian Wang* , The antimicrobial peptide Sparamosin26–54 exhibits antiviral activity against three aquatic enveloped viruses through lipid-binding-mediated virus lysis, Aquaculture, 592(2024)741160.

Bai, Y.Q., Zhang, W.B., Zheng, W.B., Meng, X.Z., Duan, Y.Y., Zhang, C., Chen, F.Y.*, Ke-Jian Wang* , A 14-amino acid cationic peptide Bolespleenin334-347 from the marine fish mudskipper Boleophthalmus pectinirostris exhibiting potent antimicrobial activity and therapeutic potential , Biochemical Pharmacology, 226(2024)116344.

Sun, H., Chen, F.Y., H., Hao, Xiong, M., Peng, H.,An, Z., Ke-Jian Wang*, Benefcial efects of AMP Scy-hepc on the gut microbiota contribute to the potential growth of Larimichthys crocea, Blue Biotechnology, (2024) 1:11

Zhang, C., Chen, F.Y.*, Bai, Y.Q., Dong, X.X., Meng, X.Z., Ke-Jian Wang* , A novel antimicrobial peptide Spasin141-165 identified from Scylla paramamosain exhibiting protection against Aeromonas hydrophila infection, Aquaculture, 591(2024)741137.

Zhou, Y., Meng, X.Y., Chen, F.Y., Xiong, M., Zhang, W.B., Ke-Jian Wang* , Newly discovered antimicrobial peptide Scyampcin44-63 from Scylla paramamosain exhibits a multitargeted candidacidal mechanism in vitro and is effective in a murine model of vaginal candidiasis, Antimicrobial Agents and Chemotherapy, 2023, aac.00022-23.

An, Z., Chen, F.Y., Hao, H., Xiong, M., Peng, H., Sun, H., Ke-Jian Wang* ,Growth- promoting effect of antimicrobial peptide Scy-hepc on mariculture large yellow croaker Larimichthys crocea and the underlying mechanism, Fish and Shellfish Immunology , 2023,108649.

Zhang, W.B., An, Z., Bai, Y.Q., Zhou, Y., Chen, F.Y. *, Ke-Jian Wang* , A novel antimicrobial peptide Scyreptin1-30 from Scylla paramamosain exhibiting potential therapy of Pseudomonas aeruginosa early infection in a mouse burn wound model, Biochemical Pharmacology, 218 (2023) 115917.

Yang Y., Chen H.Y., Hao H., Ke-Jian Wang*, The Anticancer Activity Conferred by the Mud Crab Antimicrobial Peptide Scyreprocin through Apoptosis and Membrane Disruption, International Journal of Molecular Science , 2022, 23, 5500.

Yang, Y., Chen, F.Y., Qiao, K., Zhang, H., Chen, H.Y., Ke-Jian Wang* , Two Male-Specific Antimicrobial Peptides SCY2 and Scyreprocin as Crucial Molecules Participated in the Sperm Acrosome Reaction of Mud Crab Scylla paramamosain, International Journal of Molecular Sciences, 2022, 23, 3373.